Dual role of IL-21 in megakaryopoiesis and platelet homeostasis
EHA Learning Center, Salima Benbarche, 175153
A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice
EHA Learning Center, Ana Cañete, 175154
Efferocytosis is impaired in Gaucher macrophages
EHA Learning Center, Elma Aflaki, 175155
Associations between environmental factors and hospital admissions for sickle cell disease
EHA Learning Center, Frédéric Piel, 175156
Erythrocyte survival is controlled by microRNA-142
EHA Learning Center, Natalia Rivkin, 175157
Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking
EHA Learning Center, Eduard H.T.M. Ebberink, 175158
The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer
EHA Learning Center, Anouck Wijgaerts, 175159
CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27kip1 signaling
EHA Learning Center, Feifei Zhang, 175160
Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia
EHA Learning Center, Amir T. Fathi, 175161
Lenalidomide combined with intensive chemotherapy in acute myeloid leukemia and higher-risk myelodysplastic syndrome with 5q deletion. Results of a phase II study by the Groupe Francophone Des Myélodysplasies
EHA Learning Center, lionel Adès, 175162
CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response
EHA Learning Center, Zach A. Dixon, 175163
miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study
EHA Learning Center, Anne-Laure Gagez, 175164
Inhibition of 4EBP phosphorylation mediates the cytotoxic effect of mechanistic target of rapamycin kinase inhibitors in aggressive B-cell lymphomas
EHA Learning Center, Chengfeng Bi, 175165
Safety and efficacy of obinutuzumab with CHOP or bendamustine in previously untreated follicular lymphoma
EHA Learning Center, Andrew Grigg, 175166
IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts
EHA Learning Center, Marina Bolzoni, 175167
Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients
EHA Learning Center, Michael Ghermezi, 175168
Increased age-associated mortality risk in HLA-mismatched hematopoietic stem cell transplantation
EHA Learning Center, Daniel Fürst, 175169
IFNα-Mediated Remodeling Of Endothelial Cells In The Bone Marrow Niche
EHA Learning Center, Áine M Prendergast, 171975
Iron-Heme-Bach1 Axis Is Involved In Erythroblast Adaptation To Iron Deficiency
EHA Learning Center, Masahiro Kobayashi, 171976
Small-Molecule Factor D Inhibitors Selectively Block The Alternative Pathway Of Complement In Paroxysmal Nocturnal Hemoglobinuria And Atypical Hemolytic Uremic Syndrome
EHA Learning Center, Xuan Yuan, 171977
Superior Survival Of Ex Vivo Cultured Human Reticulocytes Following Transfusion Into Mice
EHA Learning Center, Sabine Kupzig, 171978
Gfi1b Controls Integrin Signaling-Dependent Cytoskeleton Dynamics And Organization In Megakaryocytes
EHA Learning Center, Hugues Beauchemin, 171979
Progression In Patients With Low- And Intermediate-1-Risk Del(5q) Myelodysplastic Syndromes Is Predicted By A Limited Subset Of Mutations
EHA Learning Center, Christian Scharenberg, 171980
Aberrant Let7a/HMGA2 Signaling Activity With Unique Clinical Phenotype In JAK2-Mutated Myeloproliferative Neoplasms
EHA Learning Center, Chih-Cheng Chen, 171981
Phase 1 Dose-Finding Study Of Rebastinib (DCC-2036) In Patients With Relapsed Chronic Myeloid Leukemia And Acute Myeloid Leukemia
EHA Learning Center, Jorge Cortes, 171982
CEBPA–Double-Mutated Acute Myeloid Leukemia Displays A Unique Phenotypic Profile: A Reliable Screening Method And Insight Into Biological Features
EHA Learning Center, Francesco Mannelli, 171983
Tumor Suppressors BTG1 And IKZF1 Cooperate During Mouse Leukemia Development And Increase Relapse Risk In B-Cell Precursor Acute Lymphoblastic Leukemia Patients
EHA Learning Center, Blanca Scheijen, 171984
Population Pharmacokinetics Of Intravenous Erwinia Asparaginase In Pediatric Acute Lymphoblastic Leukemia Patients
EHA Learning Center, Sebastiaan D T Sassen, 171985
T Cells In Chronic Lymphocytic Leukemia Display Dysregulated Expression Of Immune Checkpoints And Activation Markers
EHA Learning Center, Marzia Palma, 171986
The Small FOXP1 Isoform Predominantly Expressed In Activated B Cell-Like Diffuse Large B-Cell Lymphoma And Full-Length FOXP1 Exert Similar Oncogenic And Transcriptional Activity In Human B Cells
EHA Learning Center, Martine van Keimpema, 171987
Factors Related To The Relative Survival Of Patients With Diffuse Large B-Cell Lymphoma In A Population-Based Study In France: Does Socio-Economic Status Have A Role?
EHA Learning Center, Sandra Le Guyader-Peyrou, 171988
Evaluation Of The Revised International Staging System In An Independent Cohort Of Unselected Patients With Multiple Myeloma
EHA Learning Center, Efstathios Kastritis, 171989
Effect Of High-Dose Plerixafor On CD34+ Cell Mobilization In Healthy Stem Cell Donors: Results Of A Randomized Crossover Trial
EHA Learning Center, Jeremy Pantin, 171990
Management of CLL patients in the front-line setting
EHA Learning Center, Delivered by Janssen, 170239
ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease
EHA Learning Center, Kyungho Kim, 167220
Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model
EHA Learning Center, Sarah Millot, 167221
The C1 and C2 domains of blood coagulation factor VIII mediate its endocytosis by dendritic cells
EHA Learning Center, Bagirath Gangadharan, 167222
Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors
EHA Learning Center, Marjorie Poggi, 167223
Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice
EHA Learning Center, Junping Xin, 167224
Immunophenotypic analysis of erythroid dysplasia in myelodysplastic syndromes. A report from the IMDSFlow working group
EHA Learning Center, Theresia M Westers, 167225
Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes
EHA Learning Center, Eline M P Cremers, 167226
Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis
EHA Learning Center, John O Mascarenhas, 167227
Distinct global binding patterns of the Wilms tumor gene 1 (WT1) −KTS and +KTS isoforms in leukemic cells
EHA Learning Center, Tove Ullmark, 167228
The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system
EHA Learning Center, Ameera Alsadeq, 167229
Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14
EHA Learning Center, Mark Hertzberg, 167230
Bone marrow findings in autoimmune lymphoproliferative syndrome with germline FAS mutation
EHA Learning Center, Yi Xie, 167231
Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs
EHA Learning Center, Rohit Mathur, 167232
Due to interleukin-6 type cytokine redundancy only glycoprotein 130 receptor blockade efficiently inhibits myeloma growth
EHA Learning Center, R. Burger, 167233
Comparable composite endpoints after HLA-matched and HLA-haploidentical transplantation with post-transplantation cyclophosphamide
EHA Learning Center, Shannon R McCurdy, 167234
Post-transplant cyclophosphamide versus anti-thymocyte globulin as graft- versus-host disease prophylaxis in haploidentical transplant
EHA Learning Center, Annalisa Ruggeri, 167235
Treatments for hematologic malignancies in contrast to those for solid cancers are associated with reduced red cell alloimmunization
EHA Learning Center, Dorothea Evers, 166069
Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia
EHA Learning Center, Chloé Latour, 166070
A plasma microRNA signature as a biomarker for acquired aplastic anemia
EHA Learning Center, Kohei Hosokawa, 166071
An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis
EHA Learning Center, Uri Rozovski, 166072
Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: an analysis by the MPN QOL International Working Group
EHA Learning Center, Holly L Geyer, 166073
A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis
EHA Learning Center, Vikas Gupta, 166074
Risk of thrombosis according to need of phlebotomies in patients with polycythemia vera treated with hydroxyurea
EHA Learning Center, Alberto Alvarez-Larrán, 166075
Pre-transplantation minimal residual disease with cytogenetic and molecular diagnostic features improves risk stratification in acute myeloid leukemia
EHA Learning Center, Betül Oran, 166076
ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype
EHA Learning Center, Shinsuke Hirabayashi, 166077
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis
EHA Learning Center, Tobias Herold, 166078
Improving results of allogeneic hematopoietic cell transplantation for adults with acute lymphoblastic leukemia in first complete remission: an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
EHA Learning Center, Sebastian Giebel, 166079
Mediastinal gray zone lymphoma: clinico-pathological characteristics and outcomes of 99 patients from the Lymphoma Study Association
EHA Learning Center, Clémentine Sarkozy, 166080
High-dose therapy and autologous stem cell transplantation in patients with POEMS syndrome: a retrospective study of the Plasma Cell Disorder sub-committee of the Chronic Malignancy Working Party of the European Society for Blood & Marrow Transplantation
EHA Learning Center, Gordon Cook, 166081
Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone
EHA Learning Center, Ana-Alicia López-Iglesias, 166082
The increase of the global donor inventory is of limited benefit to patients of non-Northwestern European descent
EHA Learning Center, Suzanna M van Walraven, 166083
Sequential regimen of clofarabine, cytosine arabinoside and reduced-intensity conditioned transplantation for primary refractory acute myeloid leukemia
EHA Learning Center, Mohamad Mohty, 166084
The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives
EHA Learning Center, Delfien J A Bogaert, 166085
EHA Learning Center, Delivered by Janssen, 165716
Role of the Intestinal Mucosa in Graft-VersusHost Disease
EHA Learning Center, Robert Jenq, 165158
Novel Agents in Chronic Lymphocytic Leukemia
EHA Learning Center, Susan O'Brien, 165159
Molecular Monitoring in Chronic Myeloid Leukemia
EHA Learning Center, Susan Branford, 165160
Minimal Residual Disease in Acute Myeloid Leukemia
EHA Learning Center, Gert Ossenkoppele, 165161
Contemporary Approaches to Iron Deficiency Anemia and the Use of IV Iron
EHA Learning Center, Michael Auerbach, 165162
Heavy Menstrual Bleeding: Work-Up and Management
EHA Learning Center, Andra H James, 165163
Reversing Direct Oral Anticoagulants
EHA Learning Center, Mark Crowther, 165164
Prevention of Strokes and other Central Nervous System Sequelae in Sickle Cell Disease without Evidence from Randomized Controlled Trials
EHA Learning Center, Michael DeBaun, 165165
Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint
EHA Learning Center, Anita Roy, 164938
Revealing eltrombopag’s promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation
EHA Learning Center, Christian A Di Buduo, 164939
Unexpected macrophage-independent dyserythropoiesis in Gaucher disease
EHA Learning Center, Nelly Reihani, 164940
Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors
EHA Learning Center, Ulrike Baschant, 164941
Response to treatment with azacitidine in children with advanced myelodysplastic syndrome prior to hematopoietic stem cell transplantation
EHA Learning Center, Nicolas Waespe, 164942
Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance)
EHA Learning Center, Christian Niederwieser, 164943
A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study
EHA Learning Center, Sabina Chiaretti, 164944
SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course
EHA Learning Center, Nili Dezorella, 164945
Ibrutinib for relapsed/refractory chronic lymphocytic leukemia: a UK and Ireland analysis of outcomes in 315 patients
EHA Learning Center, George A Follows, 164946
Real-world results of ibrutinib in patients with relapsed or refractory chronic lymphocytic leukemia: data from 95 consecutive patients treated in a compassionate use program. A study from the Swedish Chronic Lymphocytic Leukemia Group
EHA Learning Center, Maria Winqvist, 164947
Non-Hodgkin lymphoma and pre-existing conditions: spectrum, clinical characteristics and outcome in 213 children and adolescents
EHA Learning Center, Andishe Attarbaschi, 164948
Comparison of graft-versus-host disease-free, relapse-free survival according to a variety of graft sources: antithymocyte globulin and single cord blood provide favorable outcomes in some subgroups
EHA Learning Center, Yoshihiro Inamoto, 164949
Metabolic syndrome in long-term survivors of childhood acute leukemia treated without hematopoietic stem cell transplantation: an L.E.A. study
EHA Learning Center, Paul Saultier, 164950
International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia
EHA Learning Center, Nicola Gökbuget, 164951
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia
EHA Learning Center, Benjamin Neveu, 164952
Update on new agents in multiple myeloma – focus on monoclonal antibodies: An expert roundtable discussion
EHA Learning Center, Delivered by Janssen, 164424
Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura
EHA Learning Center, Wenjing Cao, 155260
Comparison of two dosing schedules for subcutaneous injections of low-dose anti-CD20 veltuzumab in relapsed immune thrombocytopenia
EHA Learning Center, Howard A Liebman, 155261
Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia
EHA Learning Center, Federica Melazzini, 155262
Genetic features of myelodysplastic syndrome and aplastic anemia in pediatric and young adult patients
EHA Learning Center, Siobán B Keel, 155263
An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation
EHA Learning Center, Paul Ferguson, 155264
Effect of age and body weight on toxicity and survival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004
EHA Learning Center, Ditte J A Løhmann, 155265
Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity
EHA Learning Center, Alice Melão, 155266
Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis
EHA Learning Center, Kebria Hezaveh, 155267