Residual Erythropoiesis Protects Against Myocardial Hemosiderosis In Transfusion-Dependent Thalassemia By Lowering Labile Plasma Iron Via Transient Generation Of Apotransferrin
EHA Learning Center, Maciej W. Garbowski, 201161
Amotosalen/Ultraviolet A Pathogen Inactivation Technology Reduces Platelet Activatability, Induces Apoptosis And Accelerates Clearance
EHA Learning Center, Simona Stivala, 201162
Bone Marrow Pathologic Abnormalities In Familial Platelet Disorder With Propensity For Myeloid Malignancy And Germline RUNX1 Mutation
EHA Learning Center, Rashmi Kanagal-Shamanna, 201163
Endotoxemia Shifts Neutrophils With TIMP-Free Gelatinase B/MMP-9 From Bone Marrow To The Periphery And Induces Systematic Upregulation Of TIMP-1
EHA Learning Center, Jennifer Vandooren, 201164
Incidence And Outcome Of Acquired Aplastic Anemia: Real-World Data From Patients Diagnosed In Sweden From 2000–2011
EHA Learning Center, Krista Vaht, 201165
Rapamycin Is Highly Effective In Murine Models Of Immune-Mediated Bone Marrow Failure
EHA Learning Center, Xingmin Feng, 201166
Prognostic Discrimination Based On The EUTOS Long-Term Survival Score Within The International Registry For Chronic Myeloid Leukemia In Children And Adolescents
EHA Learning Center, Frédéric Millot, 201167
Vosaroxin In Combination With Decitabine In Newly Diagnosed Older Patients With Acute Myeloid Leukemia Or High-Risk Myelodysplastic Syndrome
EHA Learning Center, Naval Daver, 201168
Long Non-Coding RNA Expression Profile In Cytogenetically Normal Acute Myeloid Leukemia Identifies A Distinct Signature And A New Biomarker In NPM1-Mutated Patients
EHA Learning Center, Etienne De Clara, 201169
Prolonged Versus Standard Native E. Coli Asparaginase Therapy In Childhood Acute Lymphoblastic Leukemia And Non-Hodgkin Lymphoma: Final Results Of The EORTC-CLG Randomized Phase III Trial 58951
EHA Learning Center, Veerle Mondelaers, 201170
Loss-Of-Function But Not Dominant-Negative Intragenic IKZF1 Deletions Are Associated With An Adverse Prognosis In Adult BCR-ABL-Negative Acute Lymphoblastic Leukemia
EHA Learning Center, Benjamin Kobitzsch, 201171
Secondary Malignant Neoplasms, Progression-Free Survival And Overall Survival In Patients Treated For Hodgkin Lymphoma: A Systematic Review And Meta-Analysis Of Randomized Clinical Trials
EHA Learning Center, Dennis A. Eichenauer, 201172
Exome Sequencing Identifies Recurrent BCOR Alterations And The Absence Of KLF2, TNFAIP3 And MYD88 Mutations In Splenic Diffuse Red Pulp Small B-Cell Lymphoma
EHA Learning Center, Laurent Jallades, 201173
Impact Of Prior Therapy On The Efficacy And Safety Of Oral Ixazomib-Lenalidomide-Dexamethasone Vs. Placebo-Lenalidomide-Dexamethasone In Patients With Relapsed/Refractory Multiple Myeloma In TOURMALINE-MM1
EHA Learning Center, María-Victoria Mateos, 201174
The BET Bromodomain Inhibitor CPI203 Improves Lenalidomide And Dexamethasone Activity In In Vitro And In Vivo Models Of Multiple Myeloma By Blockade Of Ikaros And MYC Signaling
EHA Learning Center, Tania Díaz, 201175
Notch2 Blockade Enhances Hematopoietic Stem Cell Mobilization And Homing
EHA Learning Center, Weihuan Wang, 201176
Characterization Of Atrial Fibrillation Adverse Events Reported In Ibrutinib Randomized Controlled Registration Trials
EHA Learning Center, Jennifer R. Brown, 201177
Case 1: M.F. McMullin - a case of high risk polycythaemia vera
EHA Learning Center, Mary Frances McMullin, 188604
Case 2: C Harrison - A case of high-risk essential thrombocythaemia refractory to hydroxyurea
EHA Learning Center, Claire Harrison, 188605
Case 3: F Cervantes - A Patient with Intermediate-2 Risk Myelofibrosis for Treatment
EHA Learning Center, Francisco Cervantes, 188606
Case 4: M Griesshammer - A 23-year old woman
EHA Learning Center, Martin Griesshammer, 188607
Case 5: M Ruggeri - A Patient with a Myeloproliferative Neoplasm who Requires Surgery
EHA Learning Center, Marco Ruggeri, 188608
Case 6: G Finazzi - A young low-risk patient with essential thrombocythaemia
EHA Learning Center, Guido Finazzi, 188609
Registration form for mentors
EHA Learning Center, Session Speakers, 196305
Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia
EHA Learning Center, James M. Otto, 196247
Long-term impact of joint bleeds in von Willebrand disease: a nested case-control study
EHA Learning Center, Karin P.M. van Galen, 196248
Comparison of risk prediction scores for venous thromboembolism in cancer patients: a prospective cohort study
EHA Learning Center, Nick van Es, 196249
Molecular analysis of myelodysplastic syndrome with isolated deletion of the long arm of chromosome 5 reveals a specific spectrum of molecular mutations with prognostic impact: a study on 123 patients and 27 genes
EHA Learning Center, Manja Meggendorfer, 196250
Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera
EHA Learning Center, Guilin Tang, 196251
Combined targeting of STAT3 and STAT5: a novel approach to overcome drug resistance in chronic myeloid leukemia
EHA Learning Center, Karoline V. Gleixner, 196252
Incidence of second primary malignancies and related mortality in patients with imatinib-treated chronic myeloid leukemia
EHA Learning Center, Gabriele Gugliotta, 196253
High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia
EHA Learning Center, Zhihong Zeng, 196254
Ultrasensitive detection of acute myeloid leukemia minimal residual disease using single molecule molecular inversion probes
EHA Learning Center, Adam Waalkes, 196255
CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo
EHA Learning Center, Jan Reimer, 196256
Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia
EHA Learning Center, Wenwen Wang, 196257
HLA-DRB1*07:01–HLA-DQA1*02:01–HLA-DQB1*02:02 haplotype is associated with a high risk of asparaginase hypersensitivity in acute lymphoblastic leukemia
EHA Learning Center, Nóra Kutszegi, 196258
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax
EHA Learning Center, Ana M. Cosialls, 196259
Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications
EHA Learning Center, Emerence Crompot, 196260
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene
EHA Learning Center, Jo-Anne van der Krogt, 196261
The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma
EHA Learning Center, Aneta Mikulasova, 196262
Treatment of Patients With Myelofibrosis and Uncontrolled Polycythemia Vera
EHA Learning Center, Delivered by Novartis, 193789
An atlas of cells with consensual nomenclature by the WP10 Morphology Faculty
EHA Learning Center, Session Speakers, 193370
Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
EHA Learning Center, Daniel Garcia-Santos, 193099
Patient-derived anti-β2GP1 antibodies recognize a peptide motif pattern and not a specific sequence of residues
EHA Learning Center, Philippe de Moerloose, 193100
Risk of cardiovascular events and pulmonary hypertension following splenectomy — a Danish population-based cohort study from 1996–2012
EHA Learning Center, Marianne Rørholt, 193101
Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia
EHA Learning Center, Douglas B Cines, 193102
Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified and reactive idiopathic hypereosinophilic syndrome
EHA Learning Center, Sa A. Wang, 193103
Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib
EHA Learning Center, Stein-Erik Gullaksen, 193104
Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study
EHA Learning Center, Delphine Rea, 193105
FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia
EHA Learning Center, Ines Pechel, 193106
Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia
EHA Learning Center, Dimitrios Papaioannou, 193107
Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells
EHA Learning Center, Elena Tibaldi, 193108
Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium
EHA Learning Center, Wendy B.C. Stevens, 193109
Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up
EHA Learning Center, Ute Hegenbart, 193110
Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation
EHA Learning Center, Maximilian Merz, 193111
Serial measurements of circulating plasma cells before and after induction therapy have an independent prognostic impact in patients with multiple myeloma undergoing upfront autologous transplantation
EHA Learning Center, Rajshekhar Chakraborty, 193112
Tbet is a critical modulator of FoxP3 expression in autoimmune graft-versus-host disease
EHA Learning Center, Shoba Amarnath, 193113
Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population
EHA Learning Center, Jens Helby, 193114
ITP and AA: Our current understanding and what the future might hold
EHA Learning Center, Delivered by Novartis, 192923
A new path to platelet production through matrix sensing
EHA Learning Center, Vittorio Abbonante, 190341
The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease
EHA Learning Center, Bérengère Koehl, 190342
Imatinib and spironolactone suppress hepcidin expression
EHA Learning Center, Katarzyna Mleczko-Sanecka, 190343
Venous thromboembolism is associated with graft-versus-host disease and increased non-relapse mortality after allogeneic hematopoietic stem cell transplantation
EHA Learning Center, Natasha Kekre, 190344
Bleeding risk of surgery and its prevention in patients with inherited platelet disorders
EHA Learning Center, Sara Orsini, 190345
Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells
EHA Learning Center, Giulia Daniele, 190346
A three-dimensional ex vivo tri-culture model mimics cell-cell interactions between acute myeloid leukemia and the vascular niche
EHA Learning Center, Laura J. Bray, 190347
Precision and prognostic value of clone-specific minimal residual disease in acute myeloid leukemia
EHA Learning Center, Pierre Hirsch, 190348
Host virus and pneumococcus-specific immune responses in high-count monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia: implications for disease progression
EHA Learning Center, Ignacio Criado, 190349
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma
EHA Learning Center, Richard A. Noble, 190350
Development of a modified prognostic index for patients with aggressive adult T-cell leukemia-lymphoma aged 70 years or younger: possible risk-adapted management strategies including allogeneic transplantation
EHA Learning Center, Shigeo Fuji, 190351
Monitoring multiple myeloma by quantification of recurrent mutations in serum
EHA Learning Center, Even Rustad, 190352
Resistin induces multidrug resistance in myeloma by inhibiting cell death and upregulating ABC transporter expression
EHA Learning Center, Jianan Pang, 190353
Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis
EHA Learning Center, Martin Granzow, 190354
Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia
EHA Learning Center, Natasha Kekre, 190355
From biology to targeted therapies in chronic lymphocytic leukemia
EHA Learning Center, Stephan Stilgenbauer, 184561
Hemophilia Treatment: Navigating Speed Bumps on the Innovation Highway
EHA Learning Center, Donna DiMichele, 184560
EHA Learning Center, Andreia Gomes, 183930
Managing CLL patients after BCR inhibitor failure
EHA Learning Center, Jeffrey Jones, 184553
Treatment Of Aggressive Lymphoma Focused On Elderly Patients
EHA Learning Center, Michael Pfreundschuh, 184545
New Treatment Approaches In Myeloma In 2017
EHA Learning Center, Jesus F. San Miguel, 184549
Harnessing T cells for Immunotherapy of AML
EHA Learning Center, Marion Subklewe, 184556
New drugs for old? What is the role of B-cell receptor pathway inhibition in the front line therapy of CLL in 2017?
EHA Learning Center, Stephen Devereux, 184552
EHA Learning Center, Silvia Bea, 183929
EHA Learning Center, Françoise Pflumio, 183931
EHA Learning Center, Katerina Tsilingiri, 183933
Relapsed aggressive lymphoma: Can we optimize the therapy
EHA Learning Center, Gilles Salles, 184544
Genetic Classification Of Myeloma For Prognostication And Treatment Selection
EHA Learning Center, Hervé Avet-Loiseau, 184548
First-line therapy for CLL in 2017
EHA Learning Center, Alessandra Tedeschi, 184551
Role of enhancers in the pathogenesis of AML
EHA Learning Center, Ruud Delwel, 184555
EHA Learning Center, Fengyan Jin, 183932
Iron Chelation in Hemoglobinopathies 
EHA Learning Center, Vip , 192910
EHA Learning Center, Gilles Salles, 183934
The Biological Basis Of Aggressive Lymphoma
EHA Learning Center, Elias Campo, 184543
Immunopathology of MM
EHA Learning Center, Nikhil Munshi, 184547
GvL / GvHD
EHA Learning Center, Fred Falkenburg, 192908
Prioritisation Therapies In CLL
EHA Learning Center, Clemens Wendtner, 184524
Indications For Transplantation In MDS
EHA Learning Center, Matteo Giovanni Della Porta, 184533
Red Cell Transfusion: When To Transfuse In Patients With Hematological Malignancies?
EHA Learning Center, Miguel Lozano Molero, 184537
Heat Shock Protein 70 (HSP70), one of the major key factors in Diamond-Blackfan anemia
EHA Learning Center, Lydie Da Costa, 184541
Pregnancy during and after treatment. Myths and reality.
EHA Learning Center, Jane Apperley, 192902